Advanced Chiropractic Logo

When Should a Medical Doctor Refer a Patient to a Chiropractor?

By Benjamin McCay, DC, CCSP

Published August 28, 2026

 

Primary care physicians see a tremendous amount of musculoskeletal pain. Back pain, neck pain, headaches, work injuries, and motor vehicle injuries may not require surgery or specialty intervention, but they still leave an important question:

What is the most appropriate conservative treatment for this patient?

Should the patient see a chiropractor? Start physical therapy? Continue normal activity and give the condition more time? Obtain imaging? Or undergo additional medical evaluation first? There is no single answer for every patient.

Chiropractic is most useful when pain, joint stiffness, restricted movement, or protective muscle guarding are prominent parts of the clinical presentation, particularly when improving comfortable movement may allow the patient to return to normal activity or progress into exercise based rehabilitation. Physical therapy may be more useful when the dominant problem is weakness, deconditioning, impaired movement control, balance, gait, or the need for progressive exercise based rehabilitation. Some patients need both.

The purpose of a chiropractic referral should not simply be to "get the patient adjusted." It should be to determine whether a musculoskeletal problem may respond to conservative manual treatment, improve function, and identify when another approach is needed.

 

Chiropractor or Physical Therapist?

There is considerable overlap between chiropractic and physical therapy. Both professions may use:

  • Exercise
  • Joint mobilization
  • Manual therapy
  • Soft tissue techniques
  • Patient education
  • Activity modification
  • Home rehabilitation

Some chiropractors provide extensive exercise rehabilitation, and some physical therapists perform spinal manipulation. Individual training and practice style matter. Nevertheless, the patient's primary functional limitation can provide a useful starting point.

Consider chiropractic when the dominant problem is:

  • Painful or restricted spinal or joint movement
  • Acute mechanical low back pain with difficulty bending, straightening, or changing position
  • Mechanical neck pain with reduced range of motion
  • Recurrent episodes of painful spinal stiffness
  • Thoracic, rib, or sacroiliac region pain associated with restricted movement
  • Protective muscle guarding that substantially limits movement
  • A musculoskeletal condition in which reducing pain and restoring movement may allow more normal activity or exercise

Consider physical therapy when the dominant problem is:

  • Weakness or significant deconditioning
  • A need for progressive strengthening
  • Balance or gait impairment
  • Neurological rehabilitation
  • Extensive movement retraining
  • Progressive postoperative rehabilitation
  • Return to demanding occupational or athletic activity
  • A need for a structured, progressively advanced exercise program

These are not absolute categories. A patient with an acutely painful and guarded lumbar spine may initially benefit from manual treatment and later need progressive strengthening. Another patient may need chiropractic and physical therapy concurrently. A different patient might fail to respond to physical therapy but respond well to chiropractic care, or vice versa. The more useful question is therefore not simply "chiropractic or physical therapy?" but rather:

What is preventing this patient from functioning normally right now?

How Can Chiropractic Reduce Pain Quickly?

The effects of spinal manipulation are sometimes explained as though a vertebra has moved "out of place" and manipulation mechanically puts it back into position. That explanation is overly simplistic and is inconsistent with contemporary pain science. Although spinal manipulation produces mechanical effects on joints and surrounding tissues, many of its immediate clinical effects are probably at least partly neurophysiological. A more useful model is:

Mechanical stimulus → altered sensory input → spinal pain modulation → changes in pain and motor output → improved ability to move

The precise contribution of each mechanism remains under investigation, but several mechanisms are biologically plausible and experimentally supported.

Afferent Input From the Manipulated Region

Spinal manipulation creates a rapid mechanical stimulus involving joints, muscles, ligaments, and other paraspinal tissues. Experimental studies have demonstrated activation of mechanosensitive afferents, including muscle spindle and Golgi tendon organ afferents, during spinal manipulation. This creates a substantial burst of mechanoreceptive sensory information entering the central nervous system.

The clinical effect is therefore unlikely to be purely mechanical. The sensory input generated by manipulation may alter spinal reflexes, motor control, and nociceptive processing.

Pain Is Modulated, Not Simply Transmitted

One of the major advances in 20th century pain science was the recognition that pain is not merely a direct readout of tissue injury. In 1965, Ronald Melzack and Patrick Wall proposed the gate control theory of pain, suggesting that nociceptive transmission within the dorsal horn could be modified by other sensory input as well as descending influences from the brain. The original model has subsequently been revised considerably, but its central contribution remains important: nociceptive information is actively modulated by the nervous system before it becomes the experience of pain. This helps explain familiar observations such as rubbing an injured area making it temporarily feel better.

Spinal manipulation produces a much stronger and more rapid mechanical sensory stimulus than simply touching the area. It is therefore reasonable that at least part of its immediate analgesic effect may result from modulation of nociceptive processing rather than from a structural correction.

Peripheral, Spinal, and Supraspinal Mechanisms

Modern models of manual therapy extend well beyond a simple spinal "gate." Mechanical stimulation may produce responses at several levels of the nervous system, including:

  • Peripheral mechanoreceptor and nociceptor activity
  • Dorsal horn processing
  • Spinal reflex activity
  • Motor neuron excitability
  • Descending pain modulatory pathways
  • Supraspinal processing of pain

Bialosky and colleagues proposed a comprehensive model in which the mechanical force of manual therapy initiates a cascade of peripheral and central neurophysiological responses that contribute to the clinical outcome. This does not mean that every proposed mechanism has been proven. It does mean that an immediate improvement in pain or movement after manipulation does not require the assumption that a vertebra was physically "put back into place."

Central Sensitization and Persistent Pain

With persistent nociceptive input, the nervous system itself can become more responsive to sensory input. Central sensitization refers to increased responsiveness of nociceptive neurons within the central nervous system. Related experimental findings may include increased temporal summation of pain, reduced pain thresholds, or impaired endogenous pain inhibition.

These phenomena have been demonstrated in subsets of patients with chronic low back pain and other persistent musculoskeletal disorders. This can help explain why the amount of pain experienced by a patient may eventually become disproportionate to the amount of detectable tissue injury. However, central sensitization should not become another catch-all diagnosis. It cannot be reliably diagnosed simply because a patient has chronic pain, and commonly used questionnaires do not directly measure sensitization of central neurons.

Likewise, it would be an overstatement to say that spinal manipulation has been proven to reverse central sensitization. A more defensible statement is that spinal manipulation and other manual treatments may temporarily alter nociceptive processing and pain sensitivity in some patients. That transient change may still be clinically useful.

Breaking the Pain, Guarding, and Restriction Cycle

A simpler clinical model may be more relevant in an acute musculoskeletal patient. Pain commonly produces protective guarding and reduced movement. Initially, this response may protect an irritated area. Sometimes, however, it becomes self-perpetuating:

Pain → protective guarding → restricted movement → continued nociceptive input → more pain and guarding

A patient with acute low back pain may therefore present moving very little, not necessarily because a joint is structurally incapable of movement, but because movement has become painful and the nervous system is protecting the region. If manual treatment reduces pain and guarding, the patient may suddenly find it easier to bend, stand, walk, or perform an exercise. The underlying tissue has obviously not healed during a 15-minute office visit. What has changed immediately is the patient's pain response, guarding, and ability to move.

This is one reason chiropractic can sometimes be particularly useful early in rehabilitation. The purpose is not simply symptom suppression. Improving comfortable movement can make it easier for the patient to resume activity and progress into exercise, strengthening, and self-management.

Which Patients Are Good Candidates for Chiropractic?

For uncomplicated musculoskeletal pain, referral does not require a highly specific structural diagnosis. A reasonable chiropractic referral may be a patient with:

1. Acute Mechanical Low Back Pain

For example:

  • Pain after lifting, bending, exercise, or prolonged activity
  • Difficulty standing upright
  • Pain transitioning from sitting to standing
  • Painful or restricted lumbar motion
  • Protective muscle guarding
  • No significant progressive neurological findings
  • No red flags suggesting fracture, infection, malignancy, or another serious disorder

This is one of the more straightforward situations in which a short trial of chiropractic care may be reasonable.

2. Recurrent Low Back Pain With Episodic Stiffness

Some patients experience recurrent episodes in which the lumbar or sacroiliac region becomes painful and difficult to move. When neurological function is stable and the presentation remains mechanical, manual treatment may help restore comfortable movement while the longer term strategy emphasizes activity, exercise, conditioning, and self-management.

3. Mechanical Neck Pain

Referral may be appropriate when neck pain is associated with:

  • Reduced cervical range of motion
  • Pain with rotation or extension
  • Upper thoracic stiffness
  • Protective muscular guarding
  • Symptoms associated with prolonged sitting or computer use
  • No concerning neurological, vascular, or systemic findings

Importantly, referral to a chiropractor does not mean that every patient will (or should) receive high velocity cervical manipulation. Treatment may instead involve mobilization, thoracic manipulation, soft tissue treatment, exercise, or another approach based on the examination.

4. Headache Associated With Neck Dysfunction

Patients with headaches accompanied by neck pain, cervical restriction, or symptoms reproducible by cervical movement may sometimes be reasonable candidates for conservative musculoskeletal treatment after concerning causes of headache have been considered.

5. Selected Radiating Arm or Leg Symptoms

The presence of radiating symptoms does not automatically exclude chiropractic care. A patient with cervical or lumbar radicular symptoms may still be appropriate for conservative management when neurological function is stable. Progressive motor weakness, spinal cord findings, bowel or bladder dysfunction, saddle anesthesia, or other evidence of significant neurological compromise changes that decision and warrants additional investigation. It is also important to recognize that radiating pain does not necessarily indicate radiculopathy.

Referred somatic pain from spinal joints, discs, muscles, and other musculoskeletal tissues can extend into an extremity without nerve root compression. Peripheral nerve entrapment can also produce symptoms that mimic cervical or lumbar radiculopathy. The distinction matters because treatment depends on the underlying mechanism. A patient with referred pain from the lumbar spine may respond differently from a patient with progressive L5 motor weakness, just as upper extremity paresthesia arising from a peripheral entrapment neuropathy requires a different approach from cervical radiculopathy.

A careful neurological and musculoskeletal examination can help determine whether conservative treatment is appropriate or whether electrodiagnostic testing, advanced imaging, or specialist referral is warranted.

Chiropractic After a Motor Vehicle Collision

A recent motor vehicle collision should not be approached exactly like uncomplicated recurrent neck or back pain. The first responsibility is to determine whether trauma has produced an injury requiring additional evaluation. Depending on the mechanism and presentation, this may include consideration of:

  • Fracture
  • Dislocation or instability
  • Significant neurological injury
  • Concussion or other traumatic brain injury
  • Radiculopathy
  • Significant ligamentous or other soft tissue injury
  • Chest, abdominal, or other nonmusculoskeletal trauma

Once serious injury has been appropriately considered, however, prolonged immobilization and avoidance of activity are generally not the goals for uncomplicated whiplash-associated disorders. Clinical guidelines support maintaining or progressively restoring activity and may incorporate exercise, mobilization or manipulation, education, and other multimodal conservative approaches. Manual therapies, exercise, education, and progressive return to normal activity can all play a role in conservative management of uncomplicated whiplash-associated disorders. Early in treatment, manual therapy may be particularly useful when pain and restricted movement are preventing the patient from comfortably progressing activity or exercise.

For example, a patient with substantial pain and guarding after a collision may initially have difficulty tolerating exercise based rehabilitation. In some cases, restoring more comfortable joint movement and reducing guarding with manual treatment can make subsequent exercise considerably easier. Conversely, once movement improves, continued passive treatment without progression toward active rehabilitation may provide diminishing benefit.

The Goal After an MVA Is Functional Recovery

Chiropractic treatment after a motor vehicle collision should not mean repeatedly manipulating the patient until the insurance claim ends. Treatment should have measurable objectives. These might include:

  • Improving cervical or lumbar range of motion
  • Reducing pain and protective guarding
  • Restoring sleep
  • Improving sitting and driving tolerance
  • Improving ability to work
  • Restoring activities of daily living
  • Progressing exercise and activity
  • Monitoring neurological findings
  • Recognizing when imaging or specialty referral is appropriate

A patient who initially cannot comfortably rotate the neck, sit for 20 minutes, or perform basic exercise may benefit from manual treatment early in the course of recovery. As motion and symptoms improve, the emphasis should progressively shift toward normal activity, exercise, and self-management.

Reassessment in Personal Injury Cases

The existence of an insurance claim does not change the physiology of healing. It can, however, make objective reassessment particularly important. Treatment should be tied to clinical improvement rather than to the duration of the legal claim. A patient should demonstrate meaningful changes such as:

  • Improved movement
  • Greater activity tolerance
  • Reduced functional disability
  • Increased work capacity
  • Improved exercise tolerance
  • Reduced neurological symptoms

If improvement plateaus, the treatment plan should change. That may mean reducing treatment frequency, transitioning toward independent exercise, adding physical therapy, obtaining imaging, requesting specialist evaluation, or reconsidering the diagnosis.

Work Injuries and Washington L&I Cases

Occupational injuries create yet another clinical context because symptom reduction is not the only objective. The practical question becomes:

Can this worker safely progress toward the physical demands of his or her job?

In Washington State, chiropractors may serve as attending providers or concurrent care providers for workers with accepted musculoskeletal conditions involving the spine or extremities. The Washington State Department of Labor & Industries specifically describes chiropractic care for injured workers as curative and rehabilitative and emphasizes functional improvement. This makes chiropractic potentially useful for more than simply providing spinal manipulation. Depending on the claim and provider, chiropractic management may include:

  • Evaluation and diagnosis of musculoskeletal conditions
  • Spinal or extremity manipulation when appropriate
  • Rehabilitative and home exercises
  • Functional assessment
  • Work restrictions
  • Monitoring progression toward return to work
  • Identification of delayed recovery
  • Coordination with physical therapy, occupational medicine, or specialists
  • Referral for advanced diagnostic imaging when appropriate

For an L&I patient, improvement in a pain score alone is not enough. A worker who reports that pain decreased from 7/10 to 4/10 but still cannot lift, bend, sit, stand, or perform the essential duties of the job has not completed rehabilitation.

Sequencing Chiropractic and PT in Work Injuries

Consider a worker with an acute lumbar strain who presents markedly guarded and has difficulty standing upright. Early treatment may focus on reducing pain and restoring comfortable movement. Once motion improves, however, the limiting factor may become:

  • Lifting capacity
  • Endurance
  • Core or lower extremity strength
  • Repeated bending tolerance
  • Work specific physical demands

At that point, progressive physical therapy or formal work rehabilitation may become more important than continued frequent manual treatment. The correct treatment may therefore change during the claim. A reasonable sequence might be:

Painful/restricted movement → manual treatment and early activity → progressive exercise → work specific rehabilitation → return to work

Not every patient requires every step. The principle is that treatment should progress according to the patient's current functional limitation rather than remain static simply because the initial treatment was helpful.

Could Chiropractor Make the Patient Worse?

This is a reasonable concern for any referring physician. No treatment is completely risk free.

Exercise can exacerbate symptoms. Medications can produce adverse effects. Injections and surgery carry their own risks. Manual treatment can also temporarily increase soreness or pain.

Most reported adverse responses following spinal manipulation are mild and transient. Serious complications have been reported, but determining their incidence is difficult because extremely rare events cannot be adequately measured in ordinary randomized clinical trials. A 2023 systematic review examining adverse event reporting in randomized trials identified 7,518 participants who received spinal manipulation and found no serious adverse events in the included trials. The authors also emphasized that adverse event reporting remained incomplete and inconsistent.

That should not be interpreted as proof that serious adverse events cannot occur. Rather, the relevant clinical question is:

Can the receiving provider identify when manipulation is inappropriate and modify treatment accordingly?

Manipulation Is Not a Single Treatment

Referring a patient to chiropractic does not obligate the chiropractor to perform high velocity manipulation. Available approaches may include:

  • High velocity, low amplitude manipulation
  • Lower force manipulation
  • Joint mobilization
  • Flexion-distraction
  • Soft tissue treatment
  • Exercise
  • Traction or other mechanical approaches
  • Activity modification
  • Or no manipulation at all

Treatment intensity should vary according to:

  • Diagnosis
  • Age
  • Bone quality
  • Recent trauma
  • Neurological findings
  • Surgical history
  • Patient tolerance
  • Comorbidities
  • Response to previous treatment

A patient who becomes progressively worse with treatment should not simply receive more of the same treatment.

The Individual Chiropractor Matters

A physician's reluctance to refer often has less to do with the theoretical value of chiropractic than with uncertainty about what will happen after the referral. That concern is legitimate. A physician should reasonably expect a chiropractor receiving referrals to:

  • Perform an appropriate history and examination
  • Develop a defensible working diagnosis
  • Recognize red flags
  • Monitor neurological findings
  • Modify treatment when necessary
  • Avoid inappropriate manipulation
  • Use functional outcomes to judge progress
  • Avoid predetermined prolonged treatment schedules
  • Communicate when progress stalls
  • Recommend another provider when that provider is more appropriate

The physician does not need to prescribe a particular chiropractic technique. A referral for evaluation and conservative treatment as appropriate is generally more useful than an instruction to manipulate a particular vertebral level.

Chiropractic After Spinal Surgery

A history of spinal surgery deserves additional caution, but it is not automatically a reason to exclude chiropractic care. The relevant questions include:

  • What surgery was performed?
  • When was it performed?
  • Is the spine healed and surgically stable?
  • Is hardware present?
  • Which segments were fused?
  • What symptoms are occurring now?
  • Are neurological findings stable?
  • Is there concern for recurrent compression, hardware failure, infection, instability, or another postoperative complication?

Recent Surgery

During postoperative healing, treatment should follow the restrictions and rehabilitation plan established by the surgeon. Routine manipulation of the operative region during this period would generally be inappropriate. If significant new symptoms develop, communication with the surgeon may be more appropriate than adding manual treatment.

Prior Fusion

A fused spinal segment has intentionally been made immobile. The objective of chiropractic treatment should therefore not be to restore motion to the fused segment. A fused segment should not be the target of manipulation intended to restore segmental motion. That does not mean the patient's entire musculoskeletal system becomes untreatable. Symptoms may arise from:

  • Muscles and connective tissues
  • Sacroiliac joints
  • Hip or shoulder regions
  • Thoracic spine
  • Cervical spine
  • Mobile segments above or below the surgical region

Treatment can be modified accordingly and may involve low force techniques, mobilization, soft tissue treatment, exercise, or treatment of other regions. The evidence regarding spinal manipulation after lumbar surgery remains limited. Systematic reviews do not provide enough high quality evidence to support broad recommendations for most postoperative situations. That uncertainty is a reason for individualized treatment and greater caution, not necessarily an absolute prohibition.

When Should Medical Evaluation Come First?

Some patients should not be referred directly for routine chiropractic treatment. Additional evaluation should take priority when there is concern for:

  • Significant fracture or instability
  • Progressive motor weakness
  • Myelopathy or spinal cord compression
  • Cauda equina syndrome
  • Spinal infection
  • Malignancy
  • Significant systemic inflammatory disease
  • Significant unexplained constitutional symptoms
  • Suspected vascular pathology
  • Major acute trauma
  • Acute postoperative complication
  • Another visceral or nonmusculoskeletal disorder presenting as spinal pain

A chiropractor evaluating a patient independently should also recognize these findings and refer when appropriate.

Does the Patient Need an MRI Before Seeing a Chiropractor?

Usually not. Routine imaging is generally unnecessary before conservative treatment of uncomplicated mechanical neck or back pain when the history and examination do not suggest serious pathology. Imaging becomes more useful when the result is likely to change management. For example:

  • Significant trauma
  • Progressive neurological deficit
  • Suspected fracture
  • Concern for infection or malignancy
  • Significant postoperative symptoms
  • Persistent symptoms when advanced imaging would affect the next treatment decision

The chiropractor can also determine during the evaluation whether imaging appears warranted.

Why Start With a Short Trial of Care?

It is rarely possible to predict with certainty which conservative treatment will work best for an individual musculoskeletal patient. A reasonable approach is therefore to select an appropriate, relatively low risk intervention and monitor the response. That is the purpose of a trial of care. The patient should not need months of treatment before anyone determines whether chiropractic is helping.

For many uncomplicated cases, there should be some indication within the early visits that the patient is responding. That improvement might include:

  • Reduced pain
  • Improved range of motion
  • Less guarding
  • Easier sitting to standing transitions
  • Improved walking
  • Greater sitting or standing tolerance
  • Reduced arm or leg symptoms
  • Improved sleep
  • Greater exercise tolerance
  • Improved work capacity

Some patients respond dramatically within only a few treatments. Others improve more gradually. Some do not respond. If the patient is not demonstrating meaningful progress, continuing the same treatment indefinitely is difficult to justify. The diagnosis and treatment strategy should then be reconsidered.

A Practical Referral Framework

For a physician deciding what to do next, a simplified framework may be useful.

1. Pain & Restricted Movement

If the patient has primarily mechanical pain, stiffness, guarding, or restricted movement without significant red flags:

Consider chiropractic evaluation.

2. Weakness & Deconditioning

If the primary limitation is weakness, balance, gait, deconditioning, or the need for progressive exercise rehabilitation:

Consider physical therapy.

3. Pain & Weakness

If pain and restricted movement prevent the patient from participating effectively in rehabilitation:

Chiropractic/manual treatment and physical therapy may be used sequentially or concurrently.

4. MVA or Other Trauma

First evaluate the traumatic presentation appropriately. If serious injury has been excluded and painful restricted movement remains:

A multimodal conservative approach that may include chiropractic care can be reasonable.

5. L&I or Occupational Injury

Ask not only whether pain is improving, but:

Is treatment restoring function and progressing the worker toward the physical requirements of the job?

Chiropractic, physical therapy, work rehabilitation, or combinations of these may be appropriate at different stages.

6. Previous Spinal Surgery

Do not assume the answer is automatically either "yes" or "no."

Clarify the procedure, surgical stability, current symptoms, and proposed treatment region and technique.

7. Progressive Neurological or Systemic Findings

Further medical evaluation comes first.

Conclusion

Physicians do not need to refer every patient with back or neck pain to a chiropractor. Nor should chiropractic necessarily be reserved until medication, physical therapy, injections, and every other conservative approach have failed. The patients most likely to benefit are often those whose primary limitation is painful, restricted musculoskeletal movement and whose presentation does not suggest a condition requiring urgent medical or surgical treatment.

The mechanisms through which manipulation may help are probably more complex than simply increasing joint motion. A rapid mechanical stimulus alters sensory input into the nervous system and may influence spinal reflexes, pain processing, motor output, and descending pain modulation. These mechanisms provide a more plausible contemporary explanation for the sometimes rapid reduction in pain and guarding after manual treatment than the traditional concept of putting a vertebra "back into place." Physical therapy may be more appropriate when progressive strengthening, conditioning, balance, gait, or extensive exercise rehabilitation is the primary need.

Some patients benefit from both. Motor vehicle injuries require appropriate consideration of trauma before routine treatment. Workers' compensation cases require attention to function and return to work capacity. Previous spinal surgery requires greater caution and modification of technique but is not necessarily an absolute contraindication.

Ultimately, the success of a chiropractic referral depends as much on the clinician as on the profession. A referring physician should be able to expect that the chiropractor will evaluate the patient independently, use an appropriate treatment technique, monitor functional improvement, recognize when the patient is not responding, and refer the patient elsewhere when another form of care becomes the better choice. That is where chiropractic fits best within modern musculoskeletal care.

Schedule an Evaluation

  1. Qaseem A, Wilt TJ, McLean RM, Forciea MA, et al. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2017;166(7):514–530.
  2. Pickar JG. Neurophysiological Effects of Spinal Manipulation. Spine J. 2002;2(5):357–371.
  3. Pickar JG, McLain RF. Responses of Mechanosensitive Afferents to Manipulation of the Lumbar Facet in the Cat. Spine. 1995;20(22):2379–2385.
  4. Bialosky JE, Bishop MD, Price DD, Robinson ME, George SZ. The Mechanisms of Manual Therapy in the Treatment of Musculoskeletal Pain: A Comprehensive Model. Man Ther. 2009;14(5):531–538.
  5. Melzack R, Wall PD. Pain Mechanisms: A New Theory. Science. 1965;150(3699):971–979.
  6. Mendell LM. Constructing and Deconstructing the Gate Theory of Pain. Pain. 2014;155(2):210–216.
  7. Seaman DR, Cleveland C III. Spinal Pain Syndromes: Nociceptive, Neuropathic, and Psychologic Mechanisms. J Manipulative Physiol Ther. 1999;22(7):458–472.
  8. Bogduk N. On the Definitions and Physiology of Back Pain, Referred Pain, and Radicular Pain. Pain. 2009;147(1-3):17–19.
  9. Fukui S, Ohseto K, Shiotani M, Ohno K, Karasawa H, Naganuma Y. Distribution of Referred Pain From the Lumbar Zygapophyseal Joints and Dorsal Rami. Clin J Pain. 1997;13(4):303–307.
  10. Simmons JW Jr, Ricketson R, McMillin JN. Painful Lumbosacral Sensory Distribution Patterns: Embryogenesis to Adulthood. Orthop Rev. 1993;22(10):1110–1118.
  11. McPhee ME, Graven-Nielsen T. Alterations in Pronociceptive and Antinociceptive Mechanisms in Patients With Low Back Pain: A Systematic Review With Meta-analysis. Pain. 2020;161(3):464–475.
  12. May S, Runge N, Aina A. Centralization and Directional Preference: An Updated Systematic Review With Synthesis of Previous Evidence. Musculoskelet Sci Pract. 2018;38:53–62.
  13. Aina A, May S, Clare H. The Centralization Phenomenon of Spinal Symptoms—A Systematic Review. Man Ther. 2004;9(3):134–143.
  14. Donelson R, Aprill C, Medcalf R, Grant W. A Prospective Study of Centralization of Lumbar and Referred Pain: A Predictor of Symptomatic Discs and Anular Competence. Spine (Phila Pa 1976). 1997;22(10):1115–1122.
  15. Bussières AE, Stewart G, Al-Zoubi F, et al. The Treatment of Neck Pain-Associated Disorders and Whiplash-Associated Disorders: A Clinical Practice Guideline. J Manipulative Physiol Ther. 2016;39(8):523–564.e27.
  16. Côté P, Wong JJ, Sutton D, et al. Management of Neck Pain and Associated Disorders: A Clinical Practice Guideline From the Ontario Protocol for Traffic Injury Management Collaboration. Eur Spine J. 2016;25(7):2000–2022.
  17. Gorrell LM, Brown BT, Engel R, Lystad RP. Reporting of Adverse Events Associated With Spinal Manipulation in Randomised Clinical Trials: An Updated Systematic Review. BMJ Open. 2023;13:e067526.
  18. Daniels CJ, Wakefield PJ, Bub GA, Toombs JD. Manipulative and Manual Therapies in the Management of Patients With Prior Lumbar Surgery: A Systematic Review. Complement Ther Clin Pract. 2021;42:101261.
  19. Washington State Department of Labor & Industries. Chiropractic Services.
  20. Washington State Department of Labor & Industries. Work Rehabilitation Guideline.
August 28, 2026
Share